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IGHV Gene Mutation Analysis

The immunoglobulin heavy chain variable region gene (IgHV) mutation status has been an established prognostic factor in patients with CLL. B-cells harboring IGHV help fight infections by making antibodies. In a disease called Chronic Lymphocytic Leukemia (CLL)...

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The immunoglobulin heavy chain variable region gene (IgHV) mutation status has been an established prognostic factor in patients with CLL. B-cells harboring IGHV help fight infections by making antibodies. In a disease called Chronic Lymphocytic Leuk...

Understanding IGHV Gene Mutation Analysis

The immunoglobulin heavy chain variable region gene (IgHV) mutation status has been an established prognostic factor in patients with CLL. B-cells harboring IGHV help fight infections by making antibodies. In a disease called Chronic Lymphocytic Leukemia (CLL), some B-cells become unhealthy and grow out of control. Doctors look at the changes in the IGHV to understand how the CLL might behave.

This is a PCR-based investigational test to determine the mutational status of IGHV by employing multiple consensus DNA pr...

What does IGHV Gene Mutation Analysis measure?

The immunoglobulin heavy chain variable region gene (IgHV) mutation status has been an established prognostic factor in patients with CLL. B-cells harboring IGHV help fight infections by making antibodies. In a disease called Chronic Lymphocytic Leukemia (CLL), some B-cells become unhealthy and grow out of control. Doctors look at the changes in the IGHV to understand how the CLL might behave.

This is a PCR-based investigational test to determine the mutational status of IGHV by employing multiple consensus DNA pri...

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