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BCR-ABL Quantitative PCR (IS Scale)
The BCR-ABL Quantitative PCR (IS Scale) is a highly sensitive molecular blood test that measures the BCR-ABL gene (a genetic mutation linked to chronic myeloid leukemia [CML] and some blood cancers) and quantifies BCR-ABL p210 fusion transcript levels on an in...
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The BCR-ABL Quantitative PCR (IS Scale) is a highly sensitive molecular blood test that measures the BCR-ABL gene (a genetic mutation linked to chronic myeloid leukemia [CML] and some blood cancers) and quantifies BCR-ABL p210 fusion transcript level...
Understanding BCR-ABL Quantitative PCR (IS Scale)
Chronic myeloid leukemia (CML) is a slow-growing blood cancer that starts in the bone marrow. It can lead to the excessive production of abnormal white blood cells. It is commonly associated with the Philadelphia chromosome, a genetic abnormality caused by a translocation between chromosomes 9 and 22. This translocation results in the formation of the BCR-ABL1 fusion gene, which produces an abnormal enzyme called BCR-ABL1 tyrosine kinase. This enzyme promotes uncontrolled cell division, leading to the progression o...
What does BCR-ABL Quantitative PCR (IS Scale) measure?
BCR-ABL Quantitative PCR (IS Scale) includes BCR-ABL Quantitative PCR (IS Scale).
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