The MPN Panel 1 is a genetic test that detects vital mutations associated with myeloproliferative neoplasms (MPNs), a type of blood cancer. It helps doctors diagnose and classify MPNs, plan treatment, and monitor disease progression.
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The MPN Panel 1 is a genetic test that detects vital mutations associated with myeloproliferative neoplasms (MPNs), a type of blood cancer. It helps doctors diagnose and classify MPNs, plan treatment, and monitor disease progression.
Understanding MPN Panel 1
Chronic myeloproliferative neoplasms (MPNs) are blood disorders in which the bone marrow produces too many red blood cells, white blood cells, or platelets.
The MPN Panel 1 is a focused genetic panel that evaluates mutations in CALR, JAK2 (exons 12–15), and MPL, which are commonly involved in MPNs. Testing these genes is important for identifying MPN types such as polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), and for providing a genetic profile to guide diagnosis, t...
What does MPN Panel 1 measure?
Contains 3 tests
MPN Panel 1 includes CALR, JAK2 (12-15), MPL.
Package contains 3 tests
Showing 3 of 3 tests
CALR is a genetic test that helps identify abnormalities in a gene called calreticulin (CALR) which is an important indicator of the development of conditions such as essential thrombocythemia (ET), a rare blood disorder and primary myelofibrosis (PMF). Abnormalities (mutations) in the CALR gene cause signs and symptoms of myeloproliferative neoplasms (MPN). This test is mostly used to analyze diagnostic and prognostic information in patients with myeloproliferative neoplasms (MPNs) when JAK2 testing is negative.
